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| Vibrio cholerae |
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Show notes:
Microbe of the episode: Streptomyces corchorusii
News item
Journal Paper:
Flaugnatti N, Isaac S, Lemos Rocha LF, Stutzmann S, Rendueles O, Stoudmann C, Vesel N, Garcia-Garcera M, Buffet A, Sana TG, Rocha EPC, Blokesch M. 2021. Human commensal gut Proteobacteria withstand type VI secretion attacks through immunity protein-independent mechanisms. Nat Commun 12:5751.
Other interesting stories:
Post questions or comments here or email to bacteriofiles@gmail.com. Thanks for listening!
Takeaways
The community of microbes in our guts is highly diverse, yet generally they all coexist relatively peacefully. Some pathogens can invade this community and cause massive disruptions. Cholera is a disease caused by a pathogen that injects its competing bacteria with toxins and disrupts the health of the gut, leading to very watery diarrhea that can quickly dehydrate victims.
This study found that some microbes commonly found harmlessly existing in the gut can resist destruction by the cholera pathogen. One of these resists by striking back with its own toxin injection system; the other creates a barrier of slime around itself that keeps the invader's toxins from reaching it. Such resistant gut microbes could help to reduce the threat of diseases such as cholera.
Flaugnatti N, Isaac S, Lemos Rocha LF, Stutzmann S, Rendueles O, Stoudmann C, Vesel N, Garcia-Garcera M, Buffet A, Sana TG, Rocha EPC, Blokesch M. 2021. Human commensal gut Proteobacteria withstand type VI secretion attacks through immunity protein-independent mechanisms. Nat Commun 12:5751.
Other interesting stories:
- Producing super-strong fibers with engineered microbes
- Some gut bacteria store some drugs inside their cells
Post questions or comments here or email to bacteriofiles@gmail.com. Thanks for listening!
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