Sunday, May 27, 2018

BacterioFiles 340 - Plasmid Promotes Plant Pathogenesis

Pathogenic Rhodococcus causing
disfigurement
From: Savory et al, eLife 6:e30925
This episode: Some bacteria living around plants can become pathogenic just by gaining a few genes!

Thanks to Skylar Fuller for her contribution!

Download Episode (9.4 MB, 10.3 minutes)

Show notes:
Microbe of the episode: Alternanthera yellow vein betasatellite

News item

Journal Paper:
Savory EA, Fuller SL, Weisberg AJ, Thomas WJ, Gordon MI, Stevens DM, Creason AL, Belcher MS, Serdani M, Wiseman MS, Grünwald NJ, Putnam ML, Chang JH. 2017. Evolutionary transitions between beneficial and phytopathogenic Rhodococcus challenge disease management. eLife 6:e30925.

Other interesting stories:
  • More gut microbe diversity could be good for arteries
  • Human gut microbes have enzymes that break down specific plant toxins (paper)
  • Gut microbes ferment fiber and modify immune response to protect mice from flu
  • Cooperation of plants and fungi breaks down if one finds alternative lifestyle (paper)
  • Disproven "arsenic in the DNA" bacterium actually has interesting arsenic detox strategies (paper)

  • Post questions or comments here or email to bacteriofiles@gmail.com. Thanks for listening!

    Subscribe: Apple Podcasts, RSS, Google Play. Support the show at Patreon, or check out the show at Twitter or Facebook.

    Episode outline:

    Monday, May 21, 2018

    BacterioFiles 339 - Medical Microbiota Measurement

    Clostridium difficile bacteria
    This episode: Fecal microbiota transplants work just as well when taken in pill form as when delivered through a tube!

    Download Episode (10.5 MB, 11.5 minutes)

    Show notes:
    Microbe of the episode: Halobacterium halobium

    News item

    Journal Paper:
    Kao D, Roach B, Silva M, Beck P, Rioux K, Kaplan GG, Chang H-J, Coward S, Goodman KJ, Xu H, Madsen K, Mason A, Wong GK-S, Jovel J, Patterson J, Louie T. 2017. Effect of Oral Capsule- vs Colonoscopy-Delivered Fecal Microbiota Transplantation on Recurrent Clostridium difficile Infection: A Randomized Clinical Trial. J Am Med Assoc 318:1985–1993.

    Other interesting stories:
  • Protein that can form prions important for protecting mice from influenza (paper)
  • Figuring out how bacteria in fruit flies kill only males
  • Healthy skin microbes could help treat eczema
  • Good gut microbe is very comfortable with immune system
  • Archaea in bogs could be good microbes for plants too (paper)

  • Post questions or comments here or email to bacteriofiles@gmail.com. Thanks for listening!

    Subscribe: Apple Podcasts, RSS, Google Play. Support the show at Patreon, or check out the show at Twitter or Facebook.

    Episode outline:

    Monday, May 14, 2018

    BacterioFiles 338 - Maverick Mouse Microbes Mitigate Maladies

    House mouse,
    Mus musculus domesticus
    This episode: Gut microbe transplants from wild mice protect lab mice from disease!

    Download Episode (9.8 MB, 10.7 minutes)

    Show notes:
    Microbe of the episode: Cabassou virus

    News item

    Journal Paper:
    Rosshart SP, Vassallo BG, Angeletti D, Hutchinson DS, Morgan AP, Takeda K, Hickman HD, McCulloch JA, Badger JH, Ajami NJ, Trinchieri G, Pardo-Manuel de Villena F, Yewdell JW, Rehermann B. 2017. Wild Mouse Gut Microbiota Promotes Host Fitness and Improves Disease Resistance. Cell 171:1015-1028.e13.

    Other interesting stories:
  • Phage cocktail can eliminate pathogen with minimal collateral damage
  • Preventive probiotics given with antibiotics can help keep C. diff away
  • Early exposure to dust and bacteria linked with less immune response to stress
  • Viruses that help wasps parasitize caterpillars also inhibit plant defenses
  • Only one microbe species can live in extremely acidic, almost boiling lake

  • Post questions or comments here or email to bacteriofiles@gmail.com. Thanks for listening!

    Subscribe: Apple Podcasts, RSS, Google Play. Support the show at Patreon, or check out the show at Twitter or Facebook.

    Episode outline: